Template Strand
Definition
The template strand is the DNA strand that serves as a guide for synthesizing an RNA molecule during transcription.
Analogy
Think of it as a blueprint used by architects. Just like how architects use blueprints to construct buildings, RNA polymerase uses the template strand to build an RNA molecule.
Related terms
Coding Strand: This is the DNA strand complementary to the template strand. It has the same sequence as the mRNA (except T in place of U) - similar to a mirror image of the blueprint.
Antisense Strand: Another name for the template strand because its sequence is opposite (or anti) to that of mRNA.
Sense Strand: Another name for coding strand because its sequence makes sense when read in 5' to 3' direction, just like how we read text from left to right in English.
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