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Active Site

Definition

The active site is the region on an enzyme where substrate molecules bind and undergo chemical reaction.

Analogy

Consider the active site as a lock and substrate molecule as key. Only specific keys (substrates) can fit into certain locks (active sites), triggering an action - opening the door or initiating chemical reactions in this case!

Related terms

Enzyme-Substrate Complex: This is formed when an enzyme binds to its substrate at its active site.

Catalyst: A substance that increases the rate of a chemical reaction without being consumed in the process; enzymes are biological catalysts.

Allosteric Site: A site on an enzyme other than the active site where molecules can bind and influence enzyme activity.

"Active Site" appears in:

Practice Questions (2)

  • The enzyme’s active site and the substrate are __ charged.
  • What inhibitor binds to the active site?


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© 2024 Fiveable Inc. All rights reserved.

AP® and SAT® are trademarks registered by the College Board, which is not affiliated with, and does not endorse this website.