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Unit 4

4.8 Multiple Choice Questions

4 min readdecember 10, 2021


AP Biology 🧬

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Multiple Choice Practice for Cellular Communication and Cell Cycle

Welcome to Unit 4 AP Biology Multiple Choice Questions! Grab some paper and a pencil 📄 to record your answers as you go. You can see how you did on the Unit 4 Practice Questions Answers and Review sheet once you're done. Don't worry, we have tons of resources available if you get stumped 😕 on a question. And if solo study is not your thing, join a group in Hours!
Not ready to take a quiz yet? Take a look at the Intro to Unit 4.
https://cdn.pixabay.com/photo/2016/11/30/12/17/cells-1872666_1280.jpg

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Image courtesy of Pixabay

Facts about the test: The AP Biology exam has 60 multiple choice questions and you will be given 1 hour 30 minutes to complete the section. That means it should take you around 15 minutes to complete 10 questions.
The following questions were not written by College Board and although they cover information outlined in the AP Biology Course and Exam Description the formatting on the exam may be different.

1. Another name for a cell signal or stimulus molecule:
A. phosphorylation cascade
B. receptor protein
C. ligand
D. kinase

2. The cell cycle contains these three distinct phases:
A. interphase, mitosis, and cytokinesis
B. G1, S, G2
C. interphase, M-phase, G0
D. G0, G1, G2

3. A sample of cells sits under a microscope. If the majority of cells show DNA in the chromatin form, what stage of the cell cycle must they be in?
A. Mitosis
B. Prophase
C. G2
D. Interphase

4. During this part of cell signaling, a message is relayed through a series of chemical changes that lead to the particular response.
A. Reception
B. Signal transduction
C. Response
D. Receptor-mediated response

5. In regards to the cell cycle, cells grow during:
A. G0, G1, G2
B. G1, S, and G2
C. G1 and G2 only
D. Interphase and Cytokinesis

6. Mitosis : cytokinesis
A. division of the cytoplasm: division of the nuclei
B. animal cells: plant cells
C. division of the nuclei: division of the cytoplasm
D. haploid cell: diploid

7. The correct order of mitotic phases:
A. prophase, anaphase, metaphase, telophase
B. anaphase, metaphase, telophase, prophase
C. telophase, anaphase, metaphase, anaphase
D. prophase, metaphase, anaphase, telophase

8. During anaphase:
A. sister chromatids separate and move to opposite poles
B. homologous chromosomes separate and move to opposite poles
C. chromosomes align vertically and exchange genetic material
D. sister chromatids align at the anaphase plate

9. What type of changes can occur during signal transduction?
A. activation or deactivation of enzymes
B. phosphorylation by kinases
C. secondary messengers amplify the signal
D. all of the these

10. How would a mutation that alters the shape of a receptor protein alter the cell signaling pathway?
A. If at least 1 receptor has not mutated, the response should stay the same
B. The ligand would enter through the plasma membrane and interact directly with the DNA
C. The ligand would most likely not bind to the receptor protein, and transduction of the signal would not happen
D. The ligand could bind to a different receptor protein and begin transduction that way

11. Secondary messengers are small molecules used within signal transduction to help amplify the signal and coordinate the signaling pathway within the cytoplasm. These are two examples of secondary messengers used in many cell types:
A. ATP and kinases
B. Ca2+ and cAMP
C. cAMP and iP2
D. ADP and ATP

12. The parathyroid gland releases PTH (parathyroid hormone) into the bloodstream ins response to low blood calcium levels. PTH signals the bones to release stored calcium into the bloodstream. What type of feedback controls the regulation and secretion of PTH?
A. negative feedback loop
B. positive feedback loop
C. signal transduction loop
D. cell cycle loop

13. In response to low blood calcium, PTH (parathyroid hormone) also interacts with cells of the intestines and the kidneys. Which conclusion about PTH and cell signaling can be made?
A. PTH secretion decreases in response to calcium levels
B. PTH secretion increases in response to calcium levels
C. Signals can only interact with one cell type
D. Signals can interact with multiple cell types

14. If a drug inhibited binding of the microtubules to the kinetochore, the cell would:
A. stop at telophase
B. stop at prophase
C. stop at anaphase
D. stop at telophase

15. The cell cycle is highly regulated by checkpoints coordinated by levels of cyclins and their interaction with CDK's. During which checkpoint does the cell get the "green light" to begin Mitosis?
A. C checkpoint
B. M checkpoint
C. G1 checkpoint

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